Semaglutide.

What semaglutide is.

Semaglutide is a GLP-1 receptor agonist. GLP-1 is a hormone your body releases after eating, and semaglutide acts on the same receptors — including sites in the pancreas and in regions of the brain involved in appetite regulation. It also slows the rate at which the stomach empties, which is part of how the GLP-1 pathway signals fullness.

It is prescription-only, taken once weekly in its injectable forms, and started at a low dose that a clinician increases over time.

Compounded or Wegovy.

Two different products.

Wegovy® is semaglutide manufactured by Novo Nordisk and approved by the FDA for chronic weight management in adults who meet defined criteria.

Compounded semaglutide is prepared by a licensed 503A pharmacy against a patient-specific prescription. Ours is compounded with glycine. Compounded medications are not reviewed or approved by the FDA for safety, effectiveness, or quality, and they are not the same product as Wegovy®. They are also not generic versions — no generic semaglutide exists.

What that means in practice: the FDA-approved product has been through a review process the compounded one has not. Your clinician can prescribe either.

Four ways to take it.

Compounded Semaglutide is the standard injectable, once weekly, dosed on a schedule your clinician sets and adjusts.

Compounded Semaglutide Microdose is the same molecule at a lower dose, compounded with vitamin B12. There is no FDA-approved dosing for microdose protocols. Some clinicians use them for patients who want a more gradual introduction.

Compounded Semaglutide Sublingual is drops held under the tongue instead of injected, for people who would rather not inject. There is no FDA-approved sublingual semaglutide.

Wegovy® is the manufacturer’s product, dispensed by a licensed U.S. pharmacy on a prescription written after a clinician review.

A clinician decides which is appropriate based on your intake — your history, your current medications, and what you tell them about how you want to start.

What’s included.

Every plan includes the medication, injection supplies where applicable, the clinician consultation and review, ongoing clinician oversight, and shipping. No membership, no hidden fees. You are not charged unless a clinician approves treatment.

Compounded options come in monthly and quarterly plans. Prices are on the cards below.

Who it isn’t for.

Semaglutide is not for everyone, and a clinician will tell you if it isn’t for you.

Do not use it if you or a family member have ever had medullary thyroid carcinoma (MTC), or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or if you have had a serious allergic reaction to semaglutide or any ingredient in the medication. It may harm an unborn baby, so it is stopped if you become pregnant and at least two months before a planned pregnancy.

Tell your clinician about past pancreatitis, gallbladder or kidney problems, slowed stomach emptying, or diabetic eye disease. Full details are on each product’s safety information page.

“Not yet” and “not for you” are real answers here, and you won’t be charged for hearing one.